However, whether an hc can become an osteoblast and contribute to the. As the matrix surrounds and isolates chondroblasts, they are called chondrocytes. Chondrocytes in the ac proliferate and secrete extracellular matrix to maintain and sustain the cartilage.
Matrix of cartilage is secreted by(a) Chondrocytes(b) Chondroblasts(c
Hyaline cartilage, including the articular cartilage of diarthrodial joints, consists of a single cellular component, the chondrocyte, which is embedded in a unique and complex.
Osteoblasts, accompanying vascular invasion, lay down endochondral bone to replace cartilage.
Hypertrophic chondrocytes instruct adjacent perichondrial cells to differentiate into osteoblasts, which secrete an extracellular matrix and form the periosteal bone collar [6]. The vertebrate skeleton is known to be formed by mesenchymal cells condensing into tissue elements (patterning phase) followed by their differentiation into cartilage. Central to maintaining cartilage health are chondrocytes, specialized cells responsible for synthesizing and regulating the extracellular matrix components of cartilage. Chondrocytes, which provide the template for the formation of most bones, are responsible for skeletal growth and articulation during postnatal life.
Embedded within the cartilage matrix are chondrocytes or cartilage cells, and the spaces they occupy are called lacunae (singular = lacuna). A layer of dense irregular connective tissue, the. Unlike most connective tissues, cartilage is avascular, meaning that it has no blood vessels supplying. For one, the primary cell types are chondrocytes as opposed to osteocytes.
This review focuses on the role of chondrocytes in cartilage formation and the progression of oa.
Cartilage is a flexible connective tissue that differs from bone in several ways.
